When we were considering which frequently asked questions about Keflex to answer at our blogsite, we found out that a lot of people are interested in how exactly does this antibiotic work and that there aren’t that many places on the web where you can find the mechanism of action of Keflex explained without oversimplifying it too much, but also not scaring the general public by using too many technical terms. Therefore, in this article, we are going to try and explain how Keflex works in a way that is going to be understandable to everyone.
Keflex is a cephalosporin antibiotic, which means that it falls in the subcategory of antibiotics known as Beta-lactam antibiotics.
This subgroup also includes penicillins, the oldest antibiotics and their derivatives. These antibiotics, unlike some other antibiotics are considered bacteriocidal, which means that they work by actually killing the bacteria. There are also antibiotics that are bacteriostatic, which means that they only prevent the multiplication of bacteria and spreading of the infection.
The way in which Keflex kills bacteria is going to be explained now. One of the main parts of the bacteria cell is the cell wall without which bacteria cannot survive.
The formation of the bacterial cell wall is a complicated process that has a few phases. However, we are only concerned with the final phase, in which involves the synthesis o something called the peptidoglycan layer of the cell walls. This layer is essential for the structural integrity of the cell and without it the cell is killed.
Keflex manages to inhibit this synthesis by inhibiting the penicillin-binding proteins which have to crosslink in order to form the peptidoglycan layer.
By doing this, the crosslinking of the PBPs is prevented, which in turn prevents the formation of the peptidoglycan layer. This means that the newly formed bacteria are going to lack the proper cell wall and that they will be easily killed by the immune system.
We hope that this short explanation has been clear enough to understand what goes on when you take Keflex for your bacterial infection. One thing that we need to add is that due to some of its characteristics, the bacteria are much less likely to become resistant to Keflex than to penicillin antibiotics.